Researchers detected levels of SARS-CoV-2 protein as early as one day after the first injection in 11 of the 13 participants. Jaramillo, Catalina. extended to treat other RNA viruses in the future. 2. In addition, the Food and Drug Administration inspects vaccine production facilities and reviews manufacturing protocols to make sure vaccine doses are of high-quality and free of contaminants. The COVID-19 pandemic necessitated the rapid production of vaccines aimed at the production of neutralizing antibodies against the COVID-19 spike protein required for the corona virus binding to target cells. The Institute is an independent nonprofit organization and architectural landmark: small by choice, intimate by nature and fearless in the face of any challenge. This is concentrated in the lungs to help you to breath. Her lab will also test Multiple vaccines are now available to help curb the threat of COVID-19, caused by the SARS-CoV-2 virus. American College of Obstetricians and Gynecologists. Structural biologist at the University of Texas at Austin. However, trillions (of these proteins) induced by the vaccine injection have the capacity to create damage in your vascular system. And the vaccines are in emergency use trials until 2023. (The chief hope, apparently, is to limit hospitalizations/death not necessarily case case counts, many of which may presumably become asymptomatic following vaccination.) Accessed 29 June 2021. Similarly, scientists studying other coronaviruses have long suspected that the spike protein contributed to damaging vascular endothelial cells, but this is the first time the process has been documented. I agree that if the mRNA vaccines themselves stimulate the human bodys cells to produce spike proteins, shouldnt there be some concern that by this process the mRNA vaccines could ultimately cause the same vascular damage? It explains why nothing is releasedhttps://www.youtube.com/watch?v=9EfToFXwx98. If the mRNA vax enters an artery or vein, youre going to experience a very bad vascular event. Accessed 29 June 2021. According to the Centers for Disease Control and Prevention, the most intensive safety monitoring in U.S. history has found that most of the reported side effects after COVID-19 vaccination are minor, such as pain at the injection site or fever. The vaccine has a limited number of spike proteins, and since its not part of a virus it cannot reproduce. Updated 29 June 2021. . Updated 9 June 2021. RNA-targeting CRISPR-Cas technology to destroy the The paper, published on April 30, 2021, in Circulation Research, also shows conclusively that COVID-19 is a vascular disease, demonstrating exactly how the SARS-CoV-2 virus damages and attacks the vascular system on a cellular level. COVID-19 spike protein damages blood vessels The "spike" proteins that the coronavirus uses to help it break into cells inflicts other damage as well, according to a new study that shines a. The spike protein is not pathogenic. 20 May 2021. Even if breaks from the enzymes which tell your immune system not to get rid of the useless mrna the body will most likely just get rid of the mrna. 10 June 2021. Previous studies have shown a similar effect when cells were exposed to the SARS-CoV-2 virus, but this is the first study to show that the damage occurs when cells are exposed to the spike protein on its own. https://www.euronews.com/2021/06/02/pfizer-covid-19-vaccine-linked-to-myocarditis-in-young-men-says-israel-s-health-ministry, Heart inflammation from Vaccine discovered . 01 Professor Juan Carlos Izpisua Belmonte is collaborating with . Circulation Research. Centers for Disease Control and Prevention. Burnham Prebys Medical Discovery Institute, Pao will develop Ogata, Alana, et al.Circulating SARS-CoV-2 Vaccine Antigen Detected in the Plasma of mRNA-1273 Vaccine Recipients. Clinical Infectious Diseases. genetics, immunology, plant biology and more. However, the model does not account for variants. It is locked in the pre-fusion state to stabilize it not to prevent binding. immunity and ii) SARS-CoV-2 treatment through viral gene Accessed 29 June 2021. Your comment is exactly the type of thing that fails the smell test. Severe adverse reactions to the vaccines have been, , a viral immunologist and associate professor at the University of Guelphs Ontario Veterinary College, during an, interview with Canadian radio personality Alex Pierson, on May 27. 1. the vaccine has an imprint (kind of like a foot print but not the foot) of the spike and an enzyme which your immune systems beta cells identify as an antigen it needs to examine. Only small fragments of the ubiquoitim proteosome protein degradation process of the induced spike protein are presented on the surface of the cell by the MHC 1 ANTIGEN presentation system. Centers for Disease Control and Prevention. To use a vaccine that induces a persons cells to manufacture a pathogen in the trillions seems foolish on the face of it. 31 Mar 2021. The highest concentration of BNT162b2 mRNA in the tested samples was 2 ng/mL a hypothetical 0.667% of the original vaccine dose being transferred in 100 mL of human milk, the study says. live viral vaccines that induce broad and long-lasting Retweeted. 10 June 2021. Hundreds of millions of COVID-19 vaccine doses have been administered safely in the United States in the last six months. There are no AC2 receptors inside the cell. Tel: (858) 453-4100 Both the American College of Obstetricians and Gynecologists and the World Health Organization encourage women who are breastfeeding to take the vaccine. Does that mean people who are vaccinated face the same health risks as COVID-19 itself? When either Sars-CoV-2 or HIV infects a person both viruses only cause an innocuous flu-like infection but like HIV, the Sars-CoV-2 spike protein can linger in the body attacking the T cells of the immune system. Find him. I have not seen any data to support what Bridle claims., Bridle, who in the radio show said hes very much pro-vaccine, says his claims are completely backed up by peer-reviewed scientific publications in well-known and well-respected scientific journals.. Instead, each carries molecular instructions, called messenger RNA (mRNA), that tell our bodies how to fight off the virus. Professor of microbiology at the Perelman School of Medicine at the University of Pennsylvania. while a professor at the Salk Institute, Holley shared the Nobel Prize for his work on how these . I dont know if this should worry me more or the same (?). . Wrapp, Daniel, et al. Exposure to this pseudovirus resulted in damage to the lungs and arteries of an animal modelproving that the spike protein alone was enough to cause disease. As mentioned, the spike protein is itself a pathogen. Some one in the scientific community must comment on the joint sites of cooperationof the research and the varied nationality of the scientists working on the project! The mixed DNA from all races might have given the virus during its replication a key for better transmission to any race. The goal of the project is to increase exposure to accurate information about COVID-19 and vaccines, while decreasing the impact of misinformation. In addition to Salks ongoing collaborative research areas that explore fundamental biological questions relevant to COVID-19, several new, coronavirus-specific projects have recently launched. And white !!!! . Ontario Veterinary College website. Its very safe, says WHOs Chief Scientist Dr. Soumya Swaminathan on a, is made possible by a grant from the Robert Wood Johnson Foundation. They travel extensively through the lymph system and a large number end up in the spleen. 1s Proposal on Voter Rolls. The short answer is absolutely not, Bridle says in the radio show. to generate a virus system that expresses a spike protein that Emails are serviced by Constant Contact. By: Express News Service All of the COVID-19 vaccines currently approved in the United States are designed to instruct human cells to make harmless spike proteins mimicking a viral protein that's used by the. 6. Yes, and thats why it can make you a little ill. Are their other unknown factors that give them natural immunity? Or more exactly between Russia,China, and the Eastern Province of Tibet. Bridle, Bryam. That if one drink from it ! if genetic alterations in pathways that control surfactant The spike protein, particularly the RBD, is therefore the main antigenic target for vaccine formulation. The premise of this study is the Spike proteins are attaching to the epithelial cells that line our circulatory system. COVID-19 vaccine for children. Statement, Canadian Paediatric Society. 27 May 2021. immunity. 14. However, vaccine-generated spike proteins cant do that fusion because they are locked in the pre-fusion shape. As the COVID-19 pandemic continues across the globe, the Salk Institute joins in efforts to understand the fundamental science behind the novel coronavirus to pave the way to treatments and cures. Theunpublished study found antibodies in the breast milk from all of the workers andminimal amounts of vaccine mRNA.. You may unsubscribe via the link found at the bottom of every email. If successful, this approach could be As weve reported, the Vaccine Adverse Event Reporting System is designed to detect potential problems thats why its there but it does not show whether the vaccines caused any of the reported issues. WHAT WE FOUND "The bottom line is the vaccine spike. See: https://www.jpost.com/health-science/could-an-mrna-vaccine-be-dangerous-in-the-long-term-649253, If these spike proteins are expressed in endothelial cells, which are found in the vascular system, brain and other organs, the protein can presumably damage that tissue in a way that may not be readily apparent. They showed that the spike protein damaged the cells by binding ACE2. Reuters Fact Check . Segments of the interview were widely spread in social media platforms in English and Spanish. We thus hypothesised that SARS-CoV-2 could use the ACE2 receptor to infect a range of nonhuman, non-bat hosts. . Canadian Covid Care Alliance. If its comforting, a little back-of-the-envelope math shows that people are at least 50,000 times more likely to die from covid than to get a serious complication from the vaccine. Why Parents, Teens, and Children Should Question the COVID-19 Vaccine. Canadian Covid Care Alliance. The Canadian Paediatric Society recommends offering the vaccine to all children and adolescents 12 years of age and older as soon as vaccine supply permits., In adocument published in June, Bridle says severe SARS-CoV-2 infections can cause damage to the cardiovascular system and neurological problems.. 02 Gerald Pao, a staff scientist in the Hunter lab, will work Updated 29 June 2021. If spike proteins are dangerous, why do the vaccines produce them? 6 Cardiology, the Affiliated Hospital of Yangzhou University (H.S.). Member of the faculty at Harvard Medical School and of Harvards Wyss Institute for Biologically Inspired Engineering. in vaccinated individuals to establish benchmarks for American College of Obstetricians and Gynecologists. While previously working on a vaccine for MERS, a disease caused by another coronavirus, McLellan and others discovered that by adding two proline molecules to the spike protein, they could lock it into its pre-fusion state, triggering a more effective immune response and preventing cell entry. 30 Mar 2021. Were on the receiving end of a very incomplete picture from mainstream media because they dont want to encourage vaccine hesitancy. This explains why the vaccine can make you a little bit ill. work will be critical to understanding the types of memory In the absence of the protein EPS8, stereocilia are too short to . It involves production of antibodies capable of covering areas across the entire spike. But theres absolutely no harm. Anyone who says there is no risk with vaccines is a liar, else why would all throughout history there have been huge billion-dollar payouts for vaccine deaths and injuries? Can I reverse it? My first instinct would be to blame any Fall/Winter COVID-19 spike on the fact that vaccine-induced immunity is temporary with some estimates as little as 6-9 months (the apparent hope, however, is that we can go 12 months between boosters). Nor is . Antisevere acute respiratory syndrome coronavirus 2 antibodies induced in breast milk after Pfizer-BioNTech/BNT162b2 vaccination. American Journal of Obstetrics & Gynecology. It is a beautiful forest with trees so tall and wide. The spike protein is unique to SARS-CoV-2 - it doesn't look like other proteins your body makes. Its very safe, says WHOs Chief Scientist Dr. Soumya Swaminathan on a podcast produced by the organization. The vaccines were supposed to be staying in the arm where the recipient was jabbed but this is now known to be false. He has designed this test, which will Vaccines, pregnancy, menstruation, lactation and fertility. Salk Institute Verified account @salkinstitute. Surfactant is a substance We found we could detect extremely low concentrations of S1 (a subunit of spike) in 11 of 13 healthy vaccinated individuals and the full spike in 3 of 13, he said in an email, noting that the technology they used is 1,000 times more sensitive than a typical antigen test, so we are really detecting minute quantities of the spike and S1 proteins. (Emphasis is his). Further studies with mutant spike proteins will also provide new insight towards the infectivity and severity of mutant SARS CoV-2 viruses.. But, he said, there is one key difference, in that the spikes encoded by the vaccines contain 2 amino acid changes that help stabilize the spike in its initial conformation and help prevent the spike from undergoing a conformational change that is required to facilitate membrane fusion.. This is because the normal spike protein must change its shape in order to achieve fusion with the ACE2 receptor. Assistant Professor Dmitry Lyumkis discusses what he loves about data and the scientific process, and which places inspire him outside the lab. It yielded the first COVID-19 vaccines. National Geographic. Possibly an end-of-life vascular event. MYTH: The COVID-19 vaccine can affect women's fertility. This is cellular biology 101. compare surfactant levels with the health outcomes of Because the vaccine produced spike proteins are locked into this state, they cannot properly bind to the ACE2 receptors in other, healthy cells. COVID-19 Vaccines While Pregnant or Breastfeeding. Updated 29 June 2021. Even if its turns out to be true that mRna spike proteins can harm your cells. Page number 45 from this PDF produced by Johns Hopkins University reveals that self-spreading vaccines already exist and are used to . Wow. 21 May 2021. But theres absolutely no harm. Researchers detected levels of SARS-CoV-2 protein as early as one day after the first injection in 11 of the 13 participants. levels in the lungs alter the course of the disease. The process prepares the body against future infection. My educated guess is this: Now that the vaccines are about to be used in kids as young as 12, I expect a more robust immune response and the presence of a better (faster) metabolism will translate into more immediate reports of adverse events among younger vaccine recipients the same group (with some exceptions!) An open space or just an open window could reduce the virus transmission. The cells genetic machinery reads the mRNAs instructions, and any leftover mRNA is ultimately destroyed by the cell. Jun 21, 2021. And I understand some clots as well, including with the Pfizer vaccine.I am asking this also because I want to get vaccinated but just like the previous comment with the autoimmune condition, I have had an autoimmune condition, the hives on and off for the past 15years (I am not that young anymore though), cause unknown although stress and some chemicals make them worse. When the cell dies, the spike protein is released.https://www.nytimes.com/interactive/2020/health/moderna-covid-19-vaccine.html, Wrong. More confirmation watch this: https://youtu.be/9EfToFXwx98?t=479. In contrast, the virus is able to produce many copies of itself in a very short time before the body can make any attempt to control it. The spike proteins from the virus and the ones generated by the vaccines are essentially the same, McLellan, the spike protein researcher at the University of Texas at Austin, told us, noting that they have the same function, structure and way of processing. Incredibly ignorant. combine CRISPR with an imaging technology, so that it will only SARS-CoV-2 Spike Protein Impairs Endothelial Function via Downregulation of ACE 2. Circulation Research. D Viral Posts Misuse VAERS Data to Make False Claims About COVID-19 Vaccines. FactCheck.org. press@salk.edu. The consent submitted will only be used for data processing originating from this website. The Pfizer and Moderna vaccines work by introducing mRNA (messenger RNA) into your muscle cells. a test to detect the presence of COVID-19 genomes in human He becomes clean !!!! The Pfizer/BioNTech and Moderna vaccines carry instructions to produce a variant of the spike protein that has been locked into whats called a prefusion-stabilized conformation. synthetic virology and chemical biology platforms, to create molecular mechanisms by which the non-structural protein . . Statement, Canadian Paediatric Society. Using a newly developed mouse model, researchers found that exposure to the SARS-CoV-2 spike protein alone was enough to induce COVID-19-like symptoms including severe inflammation in the lungs. Some such claims are. Salk Institute researchers have told us - without any ambiguity - that the spike protein is a fundamental part of the Covid-19 disease. In 1964, American biochemist Robert Holley became the first person to isolate transfer RNA (tRNA)molecules that help mRNA build proteinsand map its structure. Pharmacokinetics is the, Virus Spike Protein vs. Vaccine-Generated Spike Protein, Thats because the SARS-CoV-2 spike protein is a, . Yet, a Canadian virus immunologist recently claimed that the vaccines spike protein is a pathogenic protein, a toxin that gets into the bloodstream, then accumulates in breast milk and in a number of tissues and could lead to cardiovascular and neurological damage in adults, children and infants. The spike protein vaccine with the 2P mutation . It must first be understood by all. Is it a safe assumption that it stays in the shoulder muscle? breastfeeding after vaccinations may provide babies with protection. This conclusion suggests that vaccination-generated antibody and/or exogenous antibody against S protein not only protects the host from SARS-CoV-2 infectivity but also inhibits S protein-imposed endothelial injury. associated with more severe disease. Home - Science - Research - Coronavirus Research. Other authors on the study are Yuyang Lei and Zu-Yi Yuan of Jiaotong University in Xian, China; Cara R. Schiavon, Leonardo Andrade, and Gerald S. Shadel of Salk; Ming He, Hui Shen, Yichi Zhang, Yoshitake Cho, Mark Hepokoski, Jason X.-J. 36 out of 40 (90%) samples did not show detectable levels of vaccine mRNA. This research will uncover underlying principles and The one Dr. Malone particularly pushed is from Salk Institute, where researchers injected SARS-CoV-2 spike proteins into hamsters, which injured the lungs and blood vessels due to angiotensin . Founder and currently Executive Editor of Science-Based Medicine Steven Novella, MD is an academic clinical neurologist at the Yale University School of Medicine. will examine changes in the levels and composition of Salk researchers and collaborators show how the protein damages cells, confirming COVID-19 as a primarily vascular disease. To fuse its viral membrane with the host cell membrane it substantially changes its shape from an unstable pre-fusion state to a stable post-fusion state. The Institute is an independent nonprofit organization and architectural . Shyy, 31 March 2021, Circulation Research.DOI: 10.1161/CIRCRESAHA.121.318902. An example of data being processed may be a unique identifier stored in a cookie. The study, in which researchers administered a pseudovirus to hamsters, found the spike protein alone can damage vascular endothelial cells. But as the authors mention, the use of a pseudovirus is a limitation and findings need to be confirmed with the SARS-CoV-2 virus in the future. 17 June 2021. The paper, published on April 30, 2021, in Circulation Research, also shows conclusively that COVID-19 is a vascular disease, demonstrating exactly how the SARS-CoV-2 virus damages and attacks the vascular system on a cellular level. Science. Every cell invaded by the vaccine mRNA will eventually be destroyed by the immune system releasing spike protein. This article is a reprint of what I assume is the original source here: https://www.salk.edu/news-release/the-novel-coronavirus-spike-protein-plays-additional-key-role-in-illness/. New research: Besides initiating infection, coronavirus spike protein has key role in illness The paper also finds that Covid-19 is a vascular disease, demonstrating exactly how the SARS-CoV-2 virus damages and attacks the vascular system (comprising the blood vessels) on a cellular level. I am not as much worried about anaphylaxis but I read that the latest discoveries and treatments for hives involve anti-coagulants regarding a thrombin factor level. The point of the article is that the spike protein is dangerous, so if the vaccine is producing spike proteins, its quite a leap in logic to say that the vaccine is safe (whatever definition that is today). Reading these comments Jonathan is wrong. The point of the mRNA vaccines that you dont *need* the virus itself there to replicate because the mRNA is there to be read and the spike protein is produced. Pfaeffle, Veronika. I hope in the future humanity will be a little smarter but seeing how the future is based off you, we are F-ed. A new study co-led by Assistant Research Professor Uri Manor and UC San Diego shows that the proteins also play a key role in the disease itself. And what about those many numbers in the total population who contract the virus, recover with seemingly little damage if any to their vascular system? Since the pandemic started, his lab has been trying to develop vaccines against coronaviruses, for which he. American Journal of Obstetrics & Gynecology. 9. The CDC and FDA vaccine safety monitoring systems, which were expanded for the COVID-19 vaccines and also include a new smartphone-based reporting tool called. So clean,white,and pure. Scientists have known for a while that SARS-CoV-2's distinctive "spike" proteins help the virus infect its host by latching on to healthy cells. This is how the immune system becomes ramped up against these degraded pieces of proteins. with the Sanford Burnham Prebys Medical Discovery Institute Pierre Little | May 3, 2021 at 12:13 pm | Reply. generating protective immunity. believes that immune cells called memory B and T cells Using her knowledge of physiology and infectious disease, Professor Janelle Ayres studies ways to help patients better tolerate infections, such as pneumonia and the acute respiratory distress syndrome (ARDS) that occurs in COVID-19 patients. asking for a concerned friend who took the vaccine. 128, No. Covid makes most people not ill at all or a little ill as well.No one knows that. About three weeks ago, antivaxxers started pointing to a study from the Salk Institute as yet more "proof" that the spike protein used in COVID-19 vaccines is toxic and deadly. Dr. Fauci has openly said that it is unknown if vaccines will prevent viral shedding vs. limiting serious illness. Vol. Its internationally renowned and award-winning scientists explore the very foundations of life, seeking new understandings in neuroscience, 31 Dec 2020. 367, Issue 648313. Thank you Pierre for your explanation! For more, see How safe are the vaccines?. Ontario Veterinary College website. The studies included data from Sanofi-GlaxoSmithKline, Moderna and Pfizer-BioNTech vaccine constructs, incorporating the ancestral, Beta, Delta, Omicron BA.1 or Omicron BA.4/5 spike proteins . In this episode, we again discuss the research showing that SARS-CoV2's spike protein is sufficient on its own to cause disease. If provided, your email will not be published or shared. Your partnership allows our scientists to accelerate the pace of high-risk, high-reward discoveries that have the potential to benefit the health of all humanity-be it cancer, Alzheimers disease, climate change, infectious diseases or more. Thats because the SARS-CoV-2 spike protein is a shape-shifter. website there is limited data available on the safety and the effects of vaccination in lactating people or breastfed babies because the clinical trials didnt include people who were breastfeeding. However, it says, based on available data COVID-19 vaccines are thought not to be a risk.. There is no damage when the spike protein is just inside a cell. 02 In addition, Izpisua Belmonte led a team of multi-institution scientists to develop a new viral screening test that can not only diagnose COVID-19 in a matter of minutes with a portable, pocket-sized machine, but can also simultaneously test for other viruseslike influenzathat might be mistaken for the coronavirus. We made a big mistake, said Byram Bridle, a viral immunologist and associate professor at the University of Guelphs Ontario Veterinary College, during an interview with Canadian radio personality Alex Pierson on May 27. See: https://www.timesofisrael.com/real-world-israeli-data-shows-south-african-variant-better-at-bypassing-vaccine/. Self-spreading vaccines are not a myth. Bridle omits this information in his 37-page document, instead saying that detection of the mRNA was downplayed., Now we know the spike protein gets into circulation. The vaccines are clearly beneficial to elderly people but I would never let my children be vaxxed without long term studies. This frees the (likely many) whole and partial spike proteins inside the cell into the blood. All of the COVID-19 vaccines currently approved in the United States are designed to instruct human cells to make harmless spike proteins mimicking a viral protein thats used by the SARS-CoV-2 virus to enter cells. structures of the SARS-CoV-2 virus, together with proprietary that happened with all Covid (and other) vaccines in use today? Other parts of the immune system such as killer Tcells will destroy the spike protein infected cell with its exterior attached spike protein. The Pfizer and Moderna COVID-19 vaccines use mRNA technology to instruct a person's cells on how to create a piece of a spike protein. With this in mind, your own body making the spike protein cant be a good thing, however long they last for. Spikes and spike protein fragments move to the outside of the cell and protrude from the surface where they will be recognized by the immune system. Just like the virus. It's the same protein found on the surface of the. By submitting this form, you are granting: Salk Institute, 10010 N Torrey Pines Rd, La Jolla, California, 92037, United States, http://www.salk.edu permission to email you. In the new study, the researchers created a pseudovirus that was surrounded by SARS-CoV-2 classic crown of spike proteins, but did not contain any actual virus. Bridle is taking our results and completely misinterpreting them, said David R. Walt, a member of the faculty at Harvard Medical School and of Harvards Wyss Institute for Biologically Inspired Engineering, who co-authored a study that found circulating SARS-CoV-2 vaccine antigen in the plasma of vaccine recipients. and the World Health Organization encourage women who are breastfeeding to take the vaccine. who would not be expected to be at high risk from COVID-19 itself. what is the half -life or the time scale the mRNA and the proteins will be floating around until mRNA is degraded and the spike proteins are met by the immune system? Tissue samples showed inflammation in endothelial cells lining the pulmonary artery walls. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation.Science. 5 Immune Response Some immune cells latch onto the spikes and produce antibodiesY-shaped molecules that will recognize spike proteins and block them from getting inside other cells. The researchers will use The left images show healthy mouse lung tissue while the right images show tissue from mouse lungs exposed to the spike protein. Vol. Mar 2020. a $230,000 grant from the Ontario government. 5 Molecular and Cellular Biology Laboratory, Salk Institute for Biological Studies, La Jolla, CA (C.R.S., G.S.S.). 6 replies 0 retweets 21 likes. The Salk Institute embodies Jonas Salks mission to dare to make dreams into reality. Meanwhile, the Department of Justice is investigating myocarditis (inflammation of the heart) following cases in vaccinated service members. 02 The Lyumkis lab will also explore how the nonstructural In response we got an automatic email reply saying he cannot respond because his workload has become challenging to manage after the radio interview, which led to vicious attacks by some., In two documents prepared in response to the attention brought by the interview, Bridle says the Canadian government should be called upon to immediately halt the mass vaccination program of children and adolescents. He says there is no immediate threat of severe COVID-19 in the majority of Canadian children and adolescents, and that more safety and efficacy data is needed for the use of experimental vaccines., In May, Canada authorized the use of the Pfizer/BioNTech COVID-19 vaccine in children 12 to 15, following authorization of the vaccine in youth 16 years old and older in December. , COVID-19 Vaccination Considerations for ObstetricGynecologic Care.