Strontium is a mineral and alkaline earth metal like calcium, and it seems to work similarly to calcium in the body with its main benefit being a boost to bone health. If side effects are persistent or worsen, it is best to talk to your healthcare provider. Its a fancy word for the development of cavities! Mason, S., Hughes, N., Sufi, F., Bannon, L., Maggio, B., North, M., and Holt, J. Calcif Tissue Int 2000;67:122-7. Strontium is a trace mineral that may help keep bones strong by preventing bone loss and promoting bone growth. View abstract. View abstract. View abstract. View abstract. Calcif Tissue Int 2001;69:121-9. . JAMA 12-17-2003;290(23):3115-3121. Strontium ranelate may cause unwanted side effects such as stomach pain, diarrhea and headache. It can be found in soil and seawater as well as some foods. 2010;21(2):49-55. Pure Encapsulations Strontium (citrate) - 180 Capsules - PureFormulas Zinc: Benefits, intake, sources, deficiency, and side effects View abstract. View abstract. Overall, the results of this 2013 study performed with male subjects demonstrated that strontium ranelate supplementation appears to improve bone mineral density in men similar to the way it has been shown to help postmenopausal women struggling with osteoporosis. 1984;55(12):720-725. Some tetracycline antibiotics include demeclocycline (Declomycin), minocycline (Minocin), and tetracycline. In nature, it is found in highest amounts in the ocean and consequently in certain bony fish. If you check your calcium supplement and the supplement facts include calcium carbonate, calcium citrate, or some other name, it is simply ground rocks. It's not known if strontium. Taking strontium with quinolones might decrease their effectiveness. are clickable links to these studies. A., Preston, D. F., Wegst, A. V., and Martin, N. L. Treatment of metastatic bone pain with strontium-89. Osteoporos.Int. Low . View abstract. Results of a 2-year study. The effects of strontium ranelate on the risk of vertebral fracture in women with postmenopausal osteoporosis. Chesnut, C. H., III, Silverman, S., Andriano, K., Genant, H., Gimona, A., Harris, S., Kiel, D., LeBoff, M., Maricic, M., Miller, P., Moniz, C., Peacock, M., Richardson, P., Watts, N., and Baylink, D. A randomized trial of nasal spray salmon calcitonin in postmenopausal women with established osteoporosis: the prevent recurrence of osteoporotic fractures study. Sairanen S, Karkkainen M, Tahtela R, et al. Strontium Demystified: Everything You Wanted To Know Bone. This Dr. Axe content is medically reviewed or fact checked to ensure factually accurate information. (13). 2006;54(10):3205-3211. STRONTIUM - Uses, Side Effects, and More - WebMD Eur.J.Nucl.Med. J Clin Endocrinol Metab 1966;26:566-72. Medi-Physics, Inc., Amersham Healthcare, Arlington Heights, IL, 1998. https://www.cancerpaintherapy.com/METATECHPAGE.htm. J Clin Endocrinol Metab 2002;87:2060-6.. View abstract. 2006;34(8):608-613. Fluoride helps protect your teeth from the acid that is released when this happens. That means it may affect how strong your bones are. View abstract. (. My teeth are really strong and it feels like my bones are too. Cochrane.Database.Syst.Rev. No difference in intestinal strontium absorption after oral or IV calcitriol in children with secondary hyperparathyroidism. Drug Ther Bull. Arthritis Rheum 1998;41:81-91. I now take 680 mg strontium citrate without side effects and the fractures have stopped. Anastasilakis, A. D., Polyzos, S. A., Avramidis, A., Papatheodorou, A., and Terpos, E. Effect of strontium ranelate on lumbar spine bone mineral density in women with established osteoporosis previously treated with teriparatide. Strontium has a long list of undesirable side-effects, commonly ranging from nausea to skin irritation, and less often (fortunately), blood clots and fainting. To avoid this interaction, take strontium at least 2 hours before or after taking tetracyclines. Strontium is similar to calcium. Lets take a look at the possible health benefits of strontium. Arthritis Rheum. [Efficacy and safety of bivalos therapy for postmenopausal osteoporosis. In your diet, you get it mainly from seafood, but you can also get small amounts of it in whole milk, wheat bran, meat, poultry, and root vegetables. It is a member of the aragonite group. (4b) Another mineral containing strontium iscelestite, which is used in strontium metal alloys. Several types of calcium supplements are available are on the market in the U.S. [1] PRAC recommends suspending use of Protelos/Osseor. 2014.https://www.ema.europa.eu/en/news/prac-recommends-suspending-use-protelososseor, [2] Royal Osteoporosis Society. Unfortunately, a lot of toothpastes that contain Sr may contain a lot of other questionable ingredients, so I recommend sticking with a natural toothpaste or making your own at home such as myHomemade Probiotic Toothpaste. View abstract. Gutteridge DH, Robinson CJ, Joplin GF. [RETRACTED]. Antacids are used to decrease stomach acid. Generic drug List. D'Haese, P. C., Schrooten, I., Goodman, W. G., Cabrera, W. E., Lamberts, L. V., Elseviers, M. M., Couttenye, M. M., and De Broe, M. E. Increased bone strontium levels in hemodialysis patients with osteomalacia. Osteoporos.Int. Chesnut III, C. H., Skag, A., Christiansen, C., Recker, R., Stakkestad, J. The following doses have been studied in scientific research: Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Bird Flu Deaths Prompt U.S. to Test Vaccine in Poultry, COVID Treatment in Development Appears Promising, Marriage May Help Keep Your Blood Sugar in Check, Getting Outdoors Might Help You Take Fewer Meds, New Book: Take Control of Your Heart Disease Risk, Getting Help for a Loved One With Psychosis: It's Complicated, Health News and Information, Delivered to Your Inbox. Rev Rhum Engl Ed 1997;64(12):825-834. View abstract. View abstract. J.Bone Miner.Res. Bone 2006;38(2 Suppl 1):23-27. Nonvertebral fracture benefit from oral ibandronate administered daily or with a unique drug-free interval: Results from a pivotal phase III study in postmenopausal osteoporosis (PMO). J.Dent.Res. It does this in two ways. View abstract. View abstract. However, I dont advocate using these supplements without first reviewing the precautions listed below and talking with your health care provider. View abstract. Arthritis Rheum. The objective of this study was to determine whether strontium citrate can be used to enhance bone healing during MDO in a rabbit model. Please note the date of the last review on all articles. ", Human Nutrition, Food & Animal Sciences, University of Hawaii at Manoa: "European strontium drug spurs supplement sales in U.S.", National Osteoporosis Society: Drug treatments for osteoporosis: strontium ranelate (Protelos).. The application of Sr-89 is cost-effective, especially when compared with [opioid painkillers]. Arthritis Rheum. To avoid this interaction, take strontium at least 2 hours before or after taking quinolones. Adouble-blind, parallel, comparative study study published back in 1987 in the Journal of Periodontology looked at the effects of a toothpaste containing10 percent strontium chloride hexahydrateon 61 subjects with hypersensitivity. Groupe d'Etude de la Thrombose de Bretagne Occidentale. Shapiro, W. B., Kaslick, R. S., and Chasens, A. I. It's also known to increase osteoprotegerin that serves as the decoy for the RANKL and slows the rate of bone resorption. European Medicines Agency, 2005. N Engl J Med 2004;350:504-6. Liberman, U. View abstract. What else is it good for? The drug makes your bones stronger and lowers your chances of getting fractures. Pelletier JP, Roubille C, Raynauld JP, et al. Robinson, R. G., Spicer, J. 2000;11(1):83-91. 2014 Apr;61:48-54. doi: 10.1016/j.bone.2014.01.002. Membership to ConsumerLab.com is available online and provides immediate access to reviews of more than 1,000 products from over 400 brands. 2013 Sep 4;93(5):520-6. doi: 10.2340/00015555-1564. Strontium(89) chloride versus palliative local field radiotherapy in patients with hormonal escaped prostate cancer: a phase III study of the European Organisation for Research and Treatment of Cancer, Genitourinary Group. Ashayeri E, Omogbehin A, Sridhar R, Shankar RA. View abstract. Upset stomach and diarrhea are the most common side effects of magnesium oxide. 5 Possible (and Controversial) Health Benefits, The Foods, Supplements & Oils to Increase Bone Healing, Daniel Fast: Benefits for Your Spiritual, Emotional and Physical Health, 15 Fermented Foods for a Healthy Gut and Overall Health, 9 Proven Black Seed Oil Benefits that Boost Your Health, L-Glutamine Benefits Leaky Gut & Metabolism, Chia Seeds Benefits: The Omega-3, Protein-Packed Superfood, Apple Cider Vinegar Benefits for Weight Loss, Skin Health, Cholesterol & More. https://www.mayoclinic.org/diseases-conditions/osteoporosis/in-depth/osteoporosis-treatment/art-20046869, https://connect.mayoclinic.org/discussion/reclast-infusion/, https://americanbonehealth.org/bonesense/why-strontium-is-not-good-for-bone-health/. Symptoms modifying effect of avocado/soybean unsaponifiables (ASU) in knee osteoarthritis. Z. View abstract. Addy, M., Mostafa, P., and Newcombe, R. G. Effect of plaque of five toothpastes used in the treatment of dentin hypersensitivity. Never delay or disregard seeking professional medical advice from your doctor or other qualified health care provider because of something you have read on WebMD. My bone density has shown some improvement and no further decline. Good luck to all of you. Due to mixed research findings, its very important to speak with your doctor before supplementing with strontium to treat any health concern especially if you have Pagets disease of bone, kidney problems or any blood clotting disorders. (5a). I wont name names, but some of the most well-known toothpastes for sensitive teeth include strontium in their formulas. N Engl J Med 2004;350:459-68.. View abstract. Osteoporos.Int. Les Laboratoires Servier, 2006. Posted: 09/28/19;Revised: 09/25/20. View abstract. 2005 - 2023 WebMD LLC. Given that strontium test results are tied to the strontium ion, citrate is your best option to reap its bone-building benefits. Bone 2009;45(3):460-465. View abstract. Oncology 1998;55:377-81. Modawal, A., Ferrer, M., Choi, H. K., and Castle, J. Can and should treatments such as these be used in conjunction with strontium citrate, about which I know nothing by the way? 1 Taking magnesium oxide with food can reduce stomach troubles. Roque, I. Figuls, Martinez-Zapata, M. J., Scott-Brown, M., and Alonso-Coello, P. Radioisotopes for metastatic bone pain. Am on third brand of Strontium Citrate and doing better than on the first two. Baziotis N, Yakoumakis E, Zissimopoulos A, et al. One scientific review published in 2014 by a doctor with admitted ties to pharmaceutical makers concludes, The increased risk for cardiac events with strontium ranelate has been detected in randomized clinical trials but not in real-life observational studies. (9), Ultimately, the European Union now only endorses the use of strontium ranelate in severe cases of osteoporosis with high fracture risk. (Accessed 13 March 2004). Lo, G. H., LaValley, M., McAlindon, T., and Felson, D. T. Intra-articular hyaluronic acid in treatment of knee osteoarthritis: a meta-analysis. View abstract. J.Clin.Endocrinol.Metab 2010;95(3):1174-1181. Marquis, P., Roux, C., de la Loge, C., Diaz-Curiel, M., Cormier, C., Isaia, G., Badurski, J., Wark, J., and Meunier, P. J. Strontium ranelate prevents quality of life impairment in post-menopausal women with established vertebral osteoporosis. Cottage cheese, 1% milk fat, 1 cup 138 mg per serving. A 2007 study only involved six participants, but the researchers found thatregular toothbrushing with a strontium-supplemented toothpaste has been found to increase the strontium content in the exposed enamel, which can be an advantage in the prevention of cariogenesis. (15) What is cariogenesis? 2013 Feb;98(2):592-601. doi: 10.1210/jc.2012-3048. View abstract. Receive updates and information about Bone Health, Our Events, and Specialty Programs each month. Sr can be found in Group 2 of the periodic table. It was recommended to my sister by her doctor. View abstract. 2002;17(3):449-454. Expert.Opin.Investig.Drugs 2004;13(7):857-864. First, fluoride makes your tooth enamel stronger and less likely to suffer acid damage . Calcium is important for bone health throughout your life. View abstract. Over-the-counter dentifrices in the treatment of tooth hypersensitivity. View abstract. Maintenance of antifracture efficacy over 10 years with strontium ranelate in postmenopausal osteoporosis. No difference in intestinal strontium absorption after an oral or an intravenous 1,25(OH)2D3 bolus in normal subjects. Reginster, J. Y., Seeman, E., De Vernejoul, M. C., Adami, S., Compston, J., Phenekos, C., Devogelaer, J. P., Curiel, M. D., Sawicki, A., Goemaere, S., Sorensen, O. H., Felsenberg, D., and Meunier, P. J. Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study. Interaction of strontium and vitamin D. C R Seances Soc Biol Fil 1975;169:322-9. It seems to play a role in how your body makes new bone while it slows the breakdown of old bone. View abstract. How can Sr be used? Glucosamine therapy for treating osteoarthritis. 2008;39(4):321-325. Contact Dermatitis 2000;42(2):98-100. All rights reserved. View abstract. Strontium ranelate has risks though. Various tests for tooth sensitivity by the researchers revealed that compared to the placebo, the toothpaste containing Sr decreased dentinal hypersensitivity to a significantly greater degree. Positive results were seen within two weeks and continued for the 12 week length of the study. Have you ever heard of strontium? Cochrane.Database.Syst.Rev. Vlad, S. C., LaValley, M. P., McAlindon, T. E., and Felson, D. T. Glucosamine for pain in osteoarthritis: why do trial results differ? Male hormones (Androgens) might decrease how fast the body gets rid of strontium. When people are looking into options for osteoporosis medications, some people want to take the natural route and choose to make strontium a part of their treatment plan. View abstract. Boron seems to affect the way the . Strontium Ranelate returns to the UK as an osteoporosis drug treatment. 2019https://theros.org.uk/latest-news/2019-01-14-strontium-ranelate-returns-to-the-uk-as-an-osteoporosis-drug-treatment. (4a) In addition, strontianite is a mineral that comes from concentrations of strontium compounds, and there are several strontium compounds. View abstract. Faith123 may", "Hello @bonelady -- welcome to Connect. 11-30-1995;333(22):1437-1443. 2008;67(12):1736-1738. This is more important for postmenopausal women. am in the same situation, I wish someone from mayo could give a good answer to us. Mayo docs say it will stay in my system for up to three years. Strontium can be found in supplement form online and in health stores. Have you discussed any treatments with your doctor or have they recommended anything to you? 2010;6(12):4513-4521. Johnson, G. H., Bales, D. J., Gordon, G. E., and Powell, L. V. Clinical performance of posterior composite resin restorations. Cochrane Database Syst Rev 2006;(4):CD005326. J.Periodontol. View abstract. Is it even safe? Incidence and mortality of venous thrombosis: a population-based study. Possible side effects of radioactive Sr (Metastron) as a bone cancer treatment may include: (22). Study design: Prospective animal model study. @faith123, recently posted about having a second reclast infusion recently here, https://connect.mayoclinic.org/discussion/reclast-infusion/. Rizzoli R, Chapurlat RD, Laroche JM, et al. Why Strontium Is Not Advised for Bone Health Calcium citrate is another of the more common calcium types used in calcium supplements. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Its been interesting what research has shown to date aboutits use for osteoporosis. After a 7-day . An extensive scientific review published in 2000 concludes that: It is clear from published reports and from daily practice that injection with Sr-89 is a simple, well-tolerated treatment providing a considerable chance of good palliation of pain in patients with bone metastases from prostate cancer. It is prescribed only for those who would otherwise have no other suitable treatment to reduce their risk of broken bones.[2]. The most common supplement form is strontium citrate. Do not take it within 2 hours of ingesting calcium so I take it at bedtime. View abstract. Gillam, D. G., Newman, H. N., Davies, E. H., and Bulman, J. S. Clinical efficacy of a low abrasive dentifrice for the relief of cervical dentinal hypersensitivity. 1978;57(9-10):903. Some research shows that taking strontium ranelate helps prevent. A double-blind, randomized placebo-controlled trial published in The Journal of Clinical Endocrinology and Metabolism looked at the effects of Sr on 261 men with primary osteoporosis. With strict editorial sourcing guidelines, we only link to academic research institutions, reputable media sites and, when research is available, medically peer-reviewed studies. Apostolidis N, Paradellis T, Karydas A, et al. Effects of long-term strontium ranelate treatment on the risk of nonvertebral and vertebral fractures in postmenopausal osteoporosis: Results of a five-year, randomized, placebo-controlled trial. In 2014, the European Commission decided that strontium ranelate is only appropriate to be used in severe cases of osteoporosis andshould not be used in patients with known circulatory problems. As I said earlier, strontium is naturally found in some foods like grains and root vegetables and that amount is typically higher when there is a higher level of strontium in the growing soil. 2000;75(1-3):253-263. Clin Nucl Med 2004;29:81-5. 1990;12(4):28-33. View abstract. One study indicated that taking at least three milligrams per day of boron may have anti-inflammatory effects, which can help with osteoarthritis. Although diet is the best way to get calcium, calcium supplements may be an option if your diet falls short. 2015 Feb;74(2):422-9. doi: 10.1136/annrheumdis-2013-203989. A. Hyaluronic acid injections relieve knee pain. 2003. Peng H, Yao F, Xiong S, Wu Z, Niu G, Lu T. Strontium in public drinking water and associated public health risks in Chinese cities. View abstract. 2010;30(10):1341-1348. Les Laboratoires Servier ceased the distribution of Protelos/Osseor in August 2017. Blitzer, B. Strontium Citrate is one of the most common types of Strontium used in the dietary supplement field for bone health. Busse, B., Jobke, B., Hahn, M., Priemel, M., Niecke, M., Seitz, S., Zustin, J., Semler, J., and Amling, M. Effects of strontium ranelate administration on bisphosphonate-altered hydroxyapatite: Matrix incorporation of strontium is accompanied by changes in mineralization and microstructure. Fosomax is the formulary for my HMO, but that does not appeal to me at all. Available at: https://www.guildlink.com.au/gc/ws/servier/pi.cfm?product=sepproto. Do not be misled by marketing materials that compare them to strontium ranelate. I feel that I need something that is shown to rebuild bone (15 lumbar and thoracic vertebral compression fractures). Because strontium and calcium have very similar molecular structures, the body treats them much the same. Best Joint Supplements In 2023: Knee Pain & Joint Support. Basically, it is like you are consuming rocks. ", Beth Israel Deaconess Medical Center: "Strontium. 1986;12(9):447-454. Strontium can attach to some antibiotics called tetracyclines in the stomach. Biol.Trace Elem.Res. Consensus-based recommendations for the diagnosis and management of dentin hypersensitivity. Rheumatol.Int. Boonen, S., Laan, R. F., Barton, I. P., and Watts, N. B. Kidney Int 2000;58:981-8. Strontium Citrate side effects - Osteoporosis - Inspire Glucosamine and chondroitin for treatment of osteoarthritis: a systematic quality assessment and meta-analysis. View abstract. View abstract. Perit Dial Int 1998;18:410-4. Eur Urol 2003;44:519-26. 1992;71 Spec No:841-845. 5-10-2001;344(19):1434-1441. Results 12 weeks following cessation of 8 weeks' supervised use. View abstract. Health Phys 2004;86:193-6. Research from Europe suggests that patients on strontium ranelate may have an increased risk of heart attacks. Boron may be suitable for arthritis when taken in appropriate amounts. The treatment can sometimes cause anemia after a few weeks, so you need to have regular blood tests after the treatment. Cummings, S. R., Black, D. M., Thompson, D. E., Applegate, W. B., Barrett-Connor, E., Musliner, T. A., Palermo, L., Prineas, R., Rubin, S. M., Scott, J. C., Vogt, T., Wallace, R., Yates, A. J., and LaCroix, A. 1996;41(6):543-549. These forms are different from the ranelate compound and there have been no studies showing that they are safe or effective. Bone metastases can be extremely painful. Radiother Oncol 1994;31:33-40. Evaluation of symptomatic slow-acting drugs in osteoarthritis using the GRADE system. Some antacids include calcium carbonate (Tums, others), dihydroxyaluminum sodium carbonate (Rolaids, others), magaldrate (Riopan), aluminum hydroxide (Amphojel), aluminum hydroxide/magnesium hydroxide combinations (Maalox, Mylanta), and others.